Update on Safety Issues Related to Antihyperglycemic Therapy.
نویسندگان
چکیده
The American Diabetes Association emphasizes the importance of individualized patient care in the management of diabetes. One of the important considerations in choosing an antihyperglycemic agent is its side-effect and safety profile. This article reviews the common and clinically significant side effects of each class of agents, including ways to prevent and overcome their occurrence.
منابع مشابه
Stem Cell Therapy: the ethical issues
The ability to culture human stem cells long term, and possibly indefinitely, and to control how such cells specialise to form the different tissues of the body offers the possibility of major advances in healthcare. Stem cells have been isolated and cultured, but a great deal of research is required to develop cell lines which can generate replacement cells and tissues to treat many diseases.S...
متن کاملMetformin: an update.
Metformin is an insulin-sensitizing agent with potent antihyperglycemic properties. Its efficacy in reducing hyperglycemia in type 2 diabetes mellitus is similar to that of sulfonylureas, thiazolidinediones, and insulin. Metformin-based combination therapy is often superior to therapy with a single hypoglycemic agent. The antihyperglycemic properties of metformin are mainly attributed to suppre...
متن کاملComparison of clinical characteristics in patients with type 2 diabetes among whom different antihyperglycemic agents were prescribed as monotherapy or combination therapy by diabetes specialists
AIMS/INTRODUCTION We compared clinical characteristics in patients with type 2 diabetes for whom different antihyperglycemic agents were prescribed as monotherapy or combination therapy by diabetes specialists in Japan. MATERIALS AND METHODS Prescription data for 2005, 2008 and 2011 from diabetes specialists' patient registries identified variables related to prescription of different antihyp...
متن کاملCanagliflozin: Efficacy and Safety in Combination with Metformin Alone or with Other Antihyperglycemic Agents in Type 2 Diabetes
Metformin is typically the first pharmacologic treatment recommended for type 2 diabetes mellitus (T2DM), but many patients do not achieve glycemic control with metformin alone and eventually require combination therapy with other agents. Canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, was assessed in a comprehensive Phase 3 clinical development program consisting of ~10,000...
متن کاملGuideline Approach to Therapy in Patients With Newly Diagnosed Type 2 Diabetes
Both the prevalence and incidence of type 2 diabetes are increasing worldwide in conjunction with increased Westernization of the population’s lifestyle. Type 2 diabetes is still a leading cause of cardiovascular disease (CVD), amputation, renal failure, and blindness. The risk for microvascular complications is related to overall glycemic burden over time as measured by A1C (1,2). The UK Prosp...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Diabetes spectrum : a publication of the American Diabetes Association
دوره 27 2 شماره
صفحات -
تاریخ انتشار 2014